The GP100 is a heavy, thick gun. You may tire of that.
Weight is a two-edged sword. A heavier gun is more tiring to hold up, but absorbs more felt recoil.
It's a matter of personal taste, really. I'm a big guy with big hands, I like the heft of my GP100.
That said, if they weren't illegal in Canada, I wouldn't kick one of them 2" bbl 8 shot S&Ws like Val Kilmer had in The Salton Sea out of bed for eating crackers.