Indeed there is.Just received a 16 two days ago. The 22 and 66 are supposed to be the same razors but there is definitely a difference in the shaves for me.
My #22 is also markedly more efficient than my #16.
Enjoy your #16, it's IMHO the best one they made. The original plating on mine is nearly perfect and the shaves are actually nicer than the looks, even though it looks extremely nice.