I'd miss my B&F Blond Bader and my Rudy Vey handles, but that brush just suites me perfectly. Short loft, big knot, very dense, soft tips what more can you ask for????
Muhle Stylo with synthetic fibers (the ones prior to the new Silvertip Fiber, which I haven't tried). Softer than my best boar, and makes and gives up lather better than my badgers. Kevan says the new Silvertip Fibre is even better, which makes my hand tremble to contemplate.
If I had to pick only one... I guess it would be my Simpson Duke 2 in best. It was my only brush for 1 year and I was more than happy... till I started checking the brush forum regularly!
another vote for the Duke 2 in best. I've bought several other brushes since first buying the Duke and have yet to find one that fits my needs as well.