That is an adventure many people want to make and only a few actually do.
It will be long and it will be slower than the interstate, but I suggest driving Route 66 and getting pics of all the old tourist traps along the way.
If you get tired of the music your brought, truck stops typically have books on CD you can rent at one stop and drop off at the next. Ditto for Cracker Barrel.
Be sure to let other people know what you're planned route is and check in often.
A human being should be able to change a diaper, plan an invasion, butcher a hog, conn a ship, design a building, write a sonnet, balance accounts, build a wall, set a bone, comfort the dying, take orders, give orders, cooperate, act alone, solve equations, analyze a new problem, pitch manure, program a computer, cook a tasty meal, fight efficiently, and die gallantly. Specialization is for insects. - Robert A. Heinlein